Ion mobility spectrometry after chromatography - Accomplishments, goals, challenges

Ophthalmic Pathology: History, Accomplishments, Challenges, and Goals.

The historical part of this editorial is based in part on The History of Ophthalmology. During the 16th and 17th centuries, physicians were considered academicians and surgeons were considered craftsmen; barbers were technicians and disease was thought to be due to morbid humors. The printing press was invented, and Bartisch’s Ophthalmodouleia was the first comprehensive ophthalmology textbook....

Ion Mobility Mass Spectrometry

for more complex analysers for automated sample processing and plant control. The separation time will continue to decrease; in the past there has been limited interest in fast separations but this could change as automated sample processing is developed. Increasing use of coupled techniques such as GC-GC, liquid chromatography-GC, and supercritical Suid chromatography-GC for the separation of ...

Ion Mobility-Mass Spectrometry

Development of atmospheric pressure ionization ion mobility spectrometry and ion mobility spectrometry mass spectrometry

Evaluation of capillary liquid chromatography-electrospray ionization ion mobility spectrometry with mass spectrometry detection.

Due to the proteomics revolution, multi-dimensional separation and detection instruments are required to evaluate many peptides and proteins in single samples. In this study, electrospray ionization (ESI) ion mobility spectrometry (IMS) was evaluated as an additional separation after HPLC separations. Common HPLC mobile phase compositions (solvents, acid modifiers, and buffers) were assessed fo...